Infection and Tumor Imaging Summary of Clinical Indications
Gallium Scintigraphy in Inflammation
Gallium Scintigraphy in Malignant Disease
Indium 111 Leukocyte Scintigraphy
TC99M HMPAO Labelled Leukocyte Scintigraphy
 
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Gallium Scintigraphy in Inflammation
  • localize source of fever in Fever of Unknown Origin
  • detection of pulmonary and mediastinal inflammation/infection, especially in the immunocompromised patient
  • evaluation and follow-up of active lymphocytic or granulomatous inflammatory processes such as sarcoidosis or tuberculosis
  • diagnosing osteomyelitis and/or disk space infection
  • diagnosis and follow-up of retroperitoneal fibrosis
  • evaluation and follow-up of drug induced pulmonary toxicity (e.g. Bleomycin, Amiodarone)
Gallium Scintigraphy in Malignant Disease
  • Lymphoma
          A) Hodgkins Disease
          B) Non-Hodgkins Lymphoma
  • Additional tumors:
    • lung cancer
    • melanoma
    • hepatocellular carcinoma
    • sarcoma
    • testicular tumors
    • multiple myeloma
    • head and neck tumors
    • neuroblastoma
Gallium Scintigraphy in Inflammation
Gallium Scintigraphy in Malignant Disease
Indium 111 Leukocyte Scintigraphy
TC99M HMPAO Labelled Leukocyte Scintigraphy
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Indium 111 Leukocyte Scintigraphy for Suspected Infection / Inflammation
Indium111 Labeled White Cells
Indium 111 Leukocyte Scintigraphy
Click for larger image (55k).
  • to detect site of infection in patients with granulocytosis and fever of unknown origin
  • to localize an unkown source of sepsis and to detect additonal sites(s) of infection in patients with persistent or recurrent fever amd a known infeecton site
  • to survey for sited of abscess or infection ina febrile post-op patient without localizing signs or symptoms.
  • to detect site(s) and extent of inflammatory bowel disease
  • to detect and follow-up osteomyelitis primarily when there is existing bone pathology such as infected joint prosthesis, non-united fractures or sites of metallic hardware from prior bone surgery
  • to detect osteomyelitis in diabetic patients when degenerative or traumatic changes, neuropathic osteoarthropathy or prior osteomyelitis have caused increased bone remodeling
  • to detect osteomyelitis involving the skull in postoperative patients and to follow-up therapy
  • to detect mycotic aneurysms, vascular graft and shunt infections
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TC99M HMPAO Labelled Leukocyte Scintigraphy for Suspected Infection / Inflammation
TC99M HMPAO Labelled Leukocyte Scintigraphy
TC99M HMPAO Labelled Leukocyte Scintigraphy
Click for larger image(76k).
  • to detect suspected sites of acute inflammation / infection in the febrile patient with or without localizing signs or symptoms
  • to detect and determine the extent of inflammatory or ischemic bowel disease
  • to detect and follow-up musculoskeletal infection such as septic arthritis and osteomyelitis
   

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